Expanding the scope of anion transport studies

Drugs, metabolites, and other biologically relevant anionic species can be rapidly transported through biological membranes by a simple di(thioamide) receptor developed in our laboratory. In collaboration with the group of professor Alexander Kros from Leiden University, we have also shown that the transport kinetics of these anions can be easily quantified in both large and giant unilamellar vesicles (LUVs and GUVs).

Graphical abstract: Oxyanion transport across lipid bilayers: direct measurements in large and giant unilamellar vesicles